MY2204-3

Bronchoalveolar lavage (BAL): Exophiala dermatitidis – Shipped July 04, 2022

HISTORY

This challenge was sent as a simulated bronchoalveolar lavage (BAL) sample from a 55 year old with chronic cough and chest pain. Laboratories were expected to isolate and identify Exophiala dermatitidis.

MAIN EDUCATIONAL POINTS from MY2204-3

  • Matrix-assisted laser desorption-ionization time of flight mass spectrometry (MALDI-TOF) has been proven to be an optimal method for rapid identification of yeast belonging to the genus Exophiala.
  • Pulmonary infections with Exophiala spp. are frequently associated with Cystic Fibrosis (CF) or immunodeficiency. Prevalence of E. dermatitidis in CF patients range from 1% to 20%.

Full critique (PDF)

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