Wound: Pseudomonas aeruginosa – Shipped May 10, 2021
HISTORY
A simulated wound sample collected from 88-year-old elder care patient with a diabetic ulcer on foot was sent to category A laboratories.
Participants were expected to isolate Pseudomonas aeruginosa and perform susceptibility testing.
MAIN EDUCATIONAL POINTS from M211-4
- In addition to beta-lactamases, other resistance mechanisms (eg. porin loss, impermeability) may play a role in an organism’s resistance to various beta-lactam agents. Different resistance mechanisms may demonstrate specific resistance patterns to various antimicrobials.
- Porin loss (OprD) is the most common mechanism of imipenem resistance, however it does not usually reduce susceptibility to meropenem to the same extent – isolates with loss of the OprD porin alone will usually test as susceptible or intermediate to meropenem.
