M161-5

Bronchoalveolar lavage (BAL): Klebsiella pneumoniae – Shipped May 16, 2016

HISTORY

A simulated bronchoalveolar lavage sample collected from a 37 year old in-patient with Hodgkin’s lymphoma and pneumonia was sent to category A laboratories.

Participants were expected to isolate and identify Klebsiella pneumoniae and report susceptibility results.

MAIN EDUCATIONAL POINTS from M161-5

1. Despite emerging antimicrobial resistance in Klebsiella pneumoniae, most isolates remain susceptible to cephalosporins, aminoglycosides, trimethoprim-sulfamethoxazole and fluoroquinolones.
2. Testing and reporting agents depends on the clinical setting and local antimicrobial resistance patterns of these organisms.
3. CLSI has recently deleted cephalothin from the agents which should be considered for routine reporting on Enterobacteriaceae

Full critique (PDF)