GS214-1

Gram – CSF: 3+ (6-10/oif) neutrophils –2+ (2-10/oif) gram positive bacilli (Listeria monocytogenes) – Shipped February 07, 2022

HISTORY

A simulated CSF sample collected from a 70 year old male with confusion was sent to category A and C1 laboratories. Participants were expected to report the presence of neutrophils and gram positive bacilli.

MAIN EDUCATIONAL POINTS from GS214-1

  1. In adults, the incidence of bacterial meningitis caused by Listeria monocytogenes increases with age. For this reason, adults aged >50 years should receive an antimicrobial agent with activity against Listeria monocytogenes (ampicillin, penicillin) as part of the empiric regimen (a third-generation cephalosporin plus vancomycin) for treatment of suspected bacterial meningitis.
  2. Proper handling and interpretation of CSF specimens is critical for both patient management and public health concerns.

Full critique (PDF)

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