M192-5

Blood: Cardiobacterium hominis. Shipped August 12, 2019 FINAL RESULT

HISTORY

A simulated blood culture collected from 28-year-old male with infective endocarditis was sent to category A laboratories.

Participants were expected to isolate Cardiobacterium hominis and perform susceptibility testing.

MAIN EDUCATIONAL POINTS from M192-5

1. Slower-growing gram-negative microorganisms (usually 48–72h) isolated from blood cultures in patients suspected of infective endocarditis, and having typical morphology on Gram smear, should be suspected as belonging to the HACEK group of species.

2. Even though the HACEK group are relatively uncommon as causes of infective endocarditis compared to other bacterial species, early reporting of a suspected HACEK isolate from blood culture is important for successful treatment of these patients.

3. Antimicrobial susceptibility testing is not well standardized, and these species have reasonably typical antimicrobial susceptibility profiles.

Full critique (PDF)

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