Urine: >100 x 10^6 cfu/L Aerococcus urinae. Shipped August 12, 2019. FINAL RESULT
HISTORY
A simulated midstream urine collected from 62-year-old female with dysuria was sent to category A and C laboratories.
Participants were expected to isolate and report Aerococcus urinae.
MAIN EDUCATIONAL POINTS from M192-1
- Aerococcus urinae is infrequently isolated from urine cultures.
- Although it was previously thought to be a urinary contaminant lacking clinical significance, A. urinae has been linked to cystitis as well as complicated urinary tract infections (UTIs), especially in elderly males and immunocompromised patients.
- Although breakpoints for Aerococcus species have been added to the 2016 edition of the Clinical and Laboratory Standards Institute (CLSI) M45 – Methods for Antimicrobial Dilution and Disk Susceptibility Testing of Infrequently Isolated or Fastidious Bacteria, they are not based on a large number of isolates and should be applied with caution.
- Due to the infrequent isolation of A. urinae, clinicians likely benefit from guidance regarding its susceptibility to narrow-spectrum antibiotics such as penicillin, amoxicillin, and nitrofurantoin.
