M174-1

Throat: beta-hemolytic group A Streptococcus – Shipped February 13, 2018 –

HISTORY

A simulated throat swab collected from a 6 year old child with pharyngitis was sent to category A, B, and C laboratories.
Participants were expected to identify and report Group A Streptococcus (Streptococcus pyogenes)

MAIN EDUCATIONAL POINTS from M174-1

  1. S. pyogenes is the most common bacterial etiology of pharyngitis causing 15-30% of cases of acute pharyngitis in pediatric and adolescent patients, and 5-10% of cases of acute pharyngitis in adults.
  2. RADT-negative throat swabs from children and adolescents should receive reflex culture on BA agar or a nucleic acid amplification
    test (NAAT) to rule out S. pyogenes because of the modest sensitivity of RADTs and the potential for this pathogen to cause acute rheumatic fever (ARF) and acute glomerulonephritis (AGN) in children and adolescents following infection with S. pyogenes.

Full critique (PDF)

Posted in Clinical Bacteriology Results, critiques