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M151-1

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Midstream urine: >100×10^6cfu/L Escherichia coli – Shipped May 2015

HISTORY

A simulated midstream urine collected from a 24 years old symptomatic female outpatient, was sent to category A, B, and, C laboratories. Participants were expected to isolate and identify Escherichia coli as well as report colony count and susceptibility testing results.

MAIN EDUCATIONAL POINTS from M151-1

  1. Reporting quantification on urine culture provides important clinical information to the clinician.
  2. E. coli is the most common pathogen causing uncomplicated urinary tract infections (UTIs). Isolates are not infrequently resistant to first-line (e.g., SXT, nitrofurantoin) and second-line (e.g., ciprofloxacin, amoxicillin-clavulanate) antimicrobial agents; performing antimicrobial susceptibility testing is essential to ensure patients receive adequate therapy.

Full critique (PDF)

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